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| Sugauara,Rosângela Rumi; Sugauara,Elisângela Yumi; Kazue Otutumi,Luciana; Germano,Ricardo de Melo; Sugauara,Elaine Yae Yamashita; Quessada,Ana Maria. |
| ABSTRACT: The aim of this paper was to conduct a bibliometry search about Brazilian scientific publications that describe experimental orthopedic surgeries in dogs. It was analyzed 14 publications, and there was wide variation in the number of experimental animals, showing that there is no consensus on the appropriate number for science experiment with dogs. Most articles had been reviewed by an ethics committee (13/14, 92.85%) and only two articles (2/14; 14.28%) did not report the use of analgesic protocol. Among analgesics, morphine was the most widely used, noted in seven studies (7/14; 42.85%). In six of the articles (6/14; 42.85%), the final destination of animals was not informed, but in four experiments (4/14; 28.57%) the dogs were euthanized. In... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Analgesia; Animal experimentation; Ethics committee; Surgical orthopedic.. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000800601 |
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| Yamamoto,Marcos Kazuo; Novelli,Moacyr Domingos; Corrêa,Luciana; de Sousa,Suzana Cantanhede M; Luz,João Gualberto C. |
| Opinions about the clinical utility of platelet-rich plasma (PRP) vary, as a large number of experimental studies have questioned its efficacy. The purpose of this study was to evaluate the effects of PRP on experimental alveolar wound healing in rats. Fifty young adult male Wistar rats were divided in control and PRP groups and submitted to extraction of the right maxillary incisor. In the PRP group, blood was collected by cardiac puncture, and the socket was filled with a PRP gel. Animals were euthanized after 1, 3, 7, 14 and 30 days. Histological and histomorphometric analyses were performed at each experimental time point. Semiquantitative histological analysis showed that the PRP group exhibited significantly more collagen-matrix deposition and less... |
| Tipo: Journal article |
Palavras-chave: Tooth socket; Wound healing; Platelet-rich plasma; Animal experimentation. |
| Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000100041 |
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